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SEDATION & NEURO ED SKILL

Local Anaesthetic & Digital Block

Safe infiltration dosing, digital nerve block technique, and recognition and management of local anaesthetic systemic toxicity (LAST).

Maximum safe doses

Lidocaine

  • Plain: 3 mg/kg.
  • With adrenaline: 7 mg/kg — vasoconstriction slows systemic absorption, allowing a higher safe dose.

Bupivacaine / levobupivacaine

  • Maximum 2 mg/kg (BNF) regardless of adrenaline — the safety margin from adrenaline is less well established than for lidocaine, so do not extrapolate the lidocaine "with adrenaline" allowance.
  • Longer duration of action but slower onset than lidocaine.
Always calculate the maximum dose for this patient's weight before you draw up the syringe — don't estimate on the fly.

Dose maths — worked example

Reducing injection pain

Adrenaline in digits

This is a genuinely contested area of practice — know both the historical rationale and the modern evidence base, and be able to justify whichever approach you use.

Digital nerve block technique

  1. Dorsal two-injection ring block

    Insert the needle at the dorsolateral base of the digit on each side, angling volarwards to anaesthetise both the dorsal and volar (palmar/plantar) digital nerves on that side. Repeat on the opposite side. This blocks all four digital nerves supplying the digit.

  2. Single-injection volar subcutaneous alternative

    A single volar injection at the base of the digit, raising a subcutaneous wheal across the flexor aspect, can anaesthetise the digit with one needle pass and is often less painful — a reasonable alternative, particularly in children.

  3. Confirm the block

    Test sensation before starting the procedure; allow adequate time (several minutes) for onset before assuming failure.

Digital nerve anatomy

Recognising LAST

Managing LAST (AoA QRH 3-10, 2023)

  1. Stop injecting immediately

    Stop the local anaesthetic (remember infusion pumps) and call for help, the cardiac arrest trolley and the lipid rescue pack.

  2. Manage airway, breathing, circulation

    100% oxygen and adequate ventilation, securing the airway if needed. Avoid hypercarbia — consider mild hyperventilation. Treat seizures with small incremental doses of a benzodiazepine, and consider neuromuscular blockade if seizures cannot be controlled. Avoid vasopressin, calcium-channel blockers, beta-blockers and local anaesthetic itself as antiarrhythmics.

  3. Give lipid emulsion 20%

    1.5 mL/kg over 2–3 minutes (~100 mL at 70 kg), followed immediately by an infusion at 15 mL/kg/h. Use 20% Intralipid — propofol is not a substitute.

  4. Repeat if needed

    If cardiovascular stability is not restored or an adequate circulation deteriorates, give a repeat bolus at 5 and at 10 minutes (up to two further boluses) and, at any time after 5 minutes, double the infusion rate to 30 mL/kg/h — up to a maximum cumulative dose of 12 mL/kg (840 mL at 70 kg).

  5. In cardiac arrest, cut the adrenaline dose

    Use a reduced adrenaline dose of ≤1 microgram/kg — not the standard 1 mg. This instruction is new in the 2023 handbook and is absent from the withdrawn 2010 poster.

  6. Continue resuscitation

    CPR may need to continue for a prolonged period — prognosis with prompt lipid emulsion and good CPR is favourable. Transfer to a facility with cardiopulmonary bypass capability if recovery is not rapid.

Open the full AoA QRH LAST algorithm ↗

Pitfalls & pearls

DOPS pointers

RCEM curriculum: ED Skill. What assessors look for at each entrustment level:

1Observed only — calculates maximum dose correctly, describes technique and LAST recognition.
2aPerforms with supervisor present: correct dose calculation, aspiration technique, effective block.
2bPerforms independently with supervisor in department, including troubleshooting an incomplete block.
3Recognises and manages LAST, including lipid emulsion administration.
4Independent; teaches and supervises others.

References

  1. Joint Formulary Committee. British National Formulary — local anaesthetic monographs (lidocaine, bupivacaine).
  2. Association of Anaesthetists. Quick Reference Handbook, 3-10 Local anaesthetic toxicity, version 2, June 2023. The AAGBI 2010 safety guideline it replaced has been formally withdrawn.
  3. Williams DJ, Walker JD. A nomogram for calculating the maximum dose of local anaesthetic. Anaesthesia, 2014.
  4. Literature on adrenaline safety in digital blocks (case series, e.g. Wilhelmi et al., Krunic et al.) — routine departmental practice still varies.