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CIRCULATION DOPS · INT/HIGHER RCEM CURRICULUM

Life-Threatening Haemorrhage

Catastrophic bleeding control in the ED: external haemorrhage control, pelvic binding, major haemorrhage protocol activation, TXA and damage-control resuscitation.

Indications

Catastrophic haemorrhage control comes before airway in the <C>ABCDE approach — a patient exsanguinating from a limb will arrest before airway compromise becomes relevant.

Principles & cautions

Tourniquet use

  • Use for compressible limb haemorrhage not controlled by direct pressure, or when direct pressure is not feasible (multiple casualties, ongoing threat).
  • A properly applied tourniquet is painful — expect to give analgesia once other priorities are addressed.
  • Do not remove or loosen a pre-hospital tourniquet to "check" bleeding without a plan to control it if bleeding recurs.

Pelvic binder use

  • Apply empirically in blunt trauma with suspected pelvic injury and haemodynamic compromise — do not wait for imaging if clinically indicated.
  • Avoid repeated manual pelvic "springing" once a binder is being considered — it risks dislodging clot and is unreliable.
  • Remove or loosen only when directed by the trauma/orthopaedic team, once imaging and stability allow.
Time-critical bleeding is a race against physiology, not a diagnostic puzzle — control what you can see and feel first, then investigate.

Equipment

Combat/windlass-type tourniquet
Haemostatic gauze and wound packing material
Pelvic binder (commercial device or improvised sheet)
Permanent marker (for tourniquet time)
Wide-bore IV/IO access ×2
Major haemorrhage protocol activation pathway
Tranexamic acid for IV infusion
Prothrombin complex concentrate / vitamin K (if anticoagulated)
Warming devices, blood administration set

Tourniquet and pelvic binder placement

Step-by-step management sequence

  1. Direct pressure first

    Apply firm, sustained direct pressure to any external bleeding point as the immediate first action, while preparing further measures.

  2. Pack the wound if pressure alone fails

    For deep or junctional wounds, pack the wound cavity tightly with gauze (haemostatic gauze if available), maintaining direct pressure over the packed wound.

  3. Apply a tourniquet for uncontrolled limb haemorrhage

    Place 5–7 cm proximal to the wound (not over a joint), tighten the windlass by twisting until bleeding stops and the distal pulse is no longer palpable, then lock the windlass and secure it. Write the application time clearly on the tourniquet/patient — this drives later decisions on conversion or surgery.

  4. Apply a pelvic binder for suspected pelvic fracture

    Centre the binder over the greater trochanters (not the iliac crests) and tighten firmly but not so tight as to cause skin injury; log-roll minimally and avoid repeated pelvic springing once applied.

  5. Activate the major haemorrhage protocol

    Call it early on clinical grounds (do not wait for a falling haemoglobin) — this triggers rapid release of red cells and initiates balanced component transfusion (working towards a balanced ratio of red cells to plasma and platelets, per local protocol) and involves the blood bank, haematology and senior clinicians.

  6. Give tranexamic acid early

    In line with the CRASH-2 and CRASH-3 protocols: 1 g IV over 10 minutes, followed by a further 1 g IV infusion over 8 hours, given as early as possible and only if within 3 hours of injury — benefit diminishes and later administration may be harmful.

  7. Permissive hypotension where appropriate

    In penetrating trauma with uncontrolled haemorrhage before definitive control, a lower target blood pressure (avoiding aggressive crystalloid resuscitation that dilutes clotting factors and dislodges clot) may be used pending surgery — follow local trauma network protocols, and this does not apply once definitive haemorrhage control is achieved or in traumatic brain injury.

  8. Reverse anticoagulation

    For warfarin- or DOAC-associated major bleeding, give prothrombin complex concentrate (typically 25–50 units/kg four-factor PCC) per local policy, with IV vitamin K for warfarin; consider specific reversal agents (idarucizumab for dabigatran; andexanet alfa where available for factor Xa inhibitors) if accessible.

  9. Escalate for definitive control

    Involve surgery, interventional radiology and/or the major trauma team early — damage-control principles (control haemorrhage, restore physiology, definitive repair later) guide ongoing management.

Do not delay TXA to secure IV access elsewhere or complete other tasks — treat it as a time-critical intervention alongside haemorrhage control.

Complications & pitfalls

Tourniquet-related

  • Nerve and soft tissue injury with prolonged application — reassess regularly and aim for surgical/definitive control as soon as possible.
  • Inadequate tightening leaves venous congestion without arterial control, worsening bleeding.
  • Losing track of application time delays limb-viability decisions.

Systemic

  • Over-resuscitation with crystalloid causing dilutional coagulopathy and clot disruption.
  • Hypothermia and acidosis compounding coagulopathy ("lethal triad" with bleeding).
  • Delayed major haemorrhage protocol activation losing critical time.

Documentation

Pitfalls & pearls

DOPS pointers

RCEM curriculum: Intermediate/Higher Procedural Skill. What assessors look for at each entrustment level:

1Observed only — can describe the <C>ABCDE approach and major haemorrhage protocol pathway.
2aPerforms with the supervisor present: correct tourniquet/binder application and TXA administration.
2bPerforms with supervisor in the department: coordinates the full sequence including protocol activation and reassessment.
3Indirect supervision: leads the resuscitation team through catastrophic haemorrhage, escalates appropriately to surgery/IR.
4Independent; can teach and supervise others, including complex or multi-casualty haemorrhage scenarios.

References

  1. CRASH-2 Collaborators. Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients. Lancet 2010;376:23–32.
  2. CRASH-3 Collaborators. Effects of tranexamic acid on death, disability, vascular occlusive events in traumatic brain injury. Lancet 2019;394:1713–1723.
  3. Joint Royal Colleges Ambulance Liaison Committee / Faculty of Prehospital Care. Consensus statement on major haemorrhage and tourniquet use.
  4. National guidance on prothrombin complex concentrate for warfarin/DOAC-associated major bleeding, local trust major haemorrhage policy.
  5. RCEM Curriculum 2021 — Emergency Medicine Specialty Learning Outcomes: higher procedural skills (DOPS).