Use it only in acute vestibular syndrome
- HINTS is validated only in the acute vestibular syndrome (AVS): rapid-onset, continuous vertigo lasting >24 hours (or clearly ongoing) with nausea/vomiting, head-motion intolerance, unsteady gait — and spontaneous or gaze-evoked nystagmus present at the time of examination.
- The patient must be currently symptomatic with nystagmus. HINTS is meaningless if there is no nystagmus to characterise.
Why it matters
- In AVS, HINTS performed by a trained examiner is more sensitive than early MRI-DWI for posterior circulation stroke — small infarcts can be missed on MRI in the first 24–48 hours.
- A reassuring (peripheral) HINTS requires all three components to be peripheral. A central finding in any one component means the pattern is central.
- It is operator-dependent — if you are not confident performing and interpreting it, treat as potentially central and involve stroke/neurology / image.
The three components
HI — Head Impulse test
Ask the patient to fix on your nose. Hold the head, turn it rapidly ~10–20° to one side, and watch for a corrective (re-fixation) saccade. An abnormal test — a catch-up saccade — is the reassuring, peripheral finding (impaired vestibulo-ocular reflex on the affected side). A normal head impulse in a patient with AVS is worrying for a central cause.
N — Nystagmus
Observe in primary gaze and on lateral gaze to each side. Peripheral: unidirectional, horizontal (fast phase always the same way), worse on gaze toward the fast phase (Alexander's law), suppressed by fixation. Central: direction-changing gaze-evoked nystagmus, or vertical/torsional nystagmus.
TS — Test of Skew
Alternate-cover test: cover and uncover each eye in turn while the patient fixes ahead. A vertical corrective movement of the uncovered eye (skew deviation) is a central sign. Absence of skew is reassuring.
Peripheral vs central pattern
| Component | Peripheral (reassuring) | Central (concerning) |
|---|---|---|
| Head Impulse | Abnormal — catch-up saccade present | Normal — no saccade |
| Nystagmus | Unidirectional, horizontal, fixation-suppressed | Direction-changing, or vertical / torsional |
| Test of Skew | No skew (absent) | Vertical skew deviation present |
HINTS-plus (add hearing)
- Add a bedside hearing check (finger rub / whispered voice) — HINTS-plus.
- New unilateral hearing loss in AVS should be treated as central until proven otherwise: it can indicate an AICA territory infarct (the labyrinthine artery arises from AICA), even when the rest of HINTS looks peripheral.
- HINTS-plus improves sensitivity for stroke over HINTS alone.
Acting on the result
- Central pattern (any component), new hearing loss, or any focal neurology → treat as posterior circulation stroke until proven otherwise: MRI with DWI, and stroke/neurology involvement.
- Fully peripheral pattern (all three peripheral, no hearing loss, no other neurology) supports a peripheral vestibular cause such as vestibular neuritis — but only reliable when performed correctly in true AVS.
- Remember additional stroke risk factors and the wider differential; HINTS complements, and does not replace, overall clinical judgement.
Supervision pointers
Generic ED skills entrustment levels — not a named curriculum DOPS:
| 1 | Observed only — defines acute vestibular syndrome and when HINTS applies. |
| 2a | Performs the head impulse, characterises nystagmus and does the cover test with supervision. |
| 2b | Correctly interprets the pattern and recognises HINTS-plus hearing loss. |
| 3 | Indirect supervision; safely selects patients and escalates central patterns. |
| 4 | Independent; teaches the examination and its pitfalls. |
References
- Kattah JC, et al. HINTS to Diagnose Stroke in the Acute Vestibular Syndrome: Three-Step Bedside Oculomotor Examination More Sensitive Than Early MRI DWI. Stroke 2009;40(11):3504–3510.
- Newman-Toker DE, et al. HINTS outperforms ABCD2 to screen for stroke in acute continuous vertigo and dizziness. Acad Emerg Med 2013;20(10):986–996.
- Tarnutzer AA, et al. Does my dizzy patient have a stroke? A systematic review of bedside diagnosis in AVS. CMAJ 2011;183(9):E571–E592.